Zoom Link: https://upenn.zoom.us/j/99241403942?pwd=utmb7mJnRmc4z4whwVTCLr1f7Hi0UU.1 Meeting ID: 992 4140 3942 Passcode: 051736 Abstract: The transition of robot deployment beyond structured factories into homes, offices and busy urban spaces introduce compounded challenges of shifting task demands, unpredictable human motion, partial and noisy perception. Relying on a single monolithic planner to interpret observations, reason over high-level objectives, and compute […]
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Abstract: As filtration and separation technologies continue to improve, an emerging bottleneck arises in the differentiation between similarly sized nanometer-scale particles. Polymer brushes are densely grafted polymer chains and are viable as a surface coating to achieve improved nanometer-scale separations. Due to their stimuli-responsive nature to voltage, pH, salt concentration, etc., weak polyelectrolyte brushes are […]
Monitoring underwater ecosystems is critical for assessing marine biodiversity and tracking the ongoing impacts of global climate change. Bio-inspired soft robots present an ideal solution for these environments, leveraging morphological mimicry, physical compliance, and low-acoustic locomotion to enable the non-disruptive observation of aquatic life. In this thesis, we investigate a squid-inspired, jet-propelled robotic platform, presenting […]
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Environmental fluid mechanics seeks to understand how exchanges of momentum, heat, water, and tracers between the Earth's surface and the atmosphere influence the structure and evolution of the atmospheric boundary layer and, ultimately, weather and climate. In this talk, I will provide an overview of research at the interface of fluid mechanics, atmospheric science, and […]
Metastasis remains the leading cause of cancer-related mortality. To spread, cancer cells escape the primary tumor site, traverse heterogeneous tissues and the extracellular matrix, evade the immune system, and establish secondary tumors. Throughout this process, cells constantly interact with microenvironments that resist, relax, and remodel in response to force. These mechanical interactions shape how cells […]
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Abstract: Tissues stiffen in aging, fibrosis, cancer, and injury, yet how these physical changes are recorded inside the nucleus has remained poorly understood. This dissertation establishes that matrix stiffness is not merely sensed at the cell surface and relayed biochemically inward. It is encoded directly in chromatin architecture, accumulated over time, and expressed as distinct […]
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Zoom: https://upenn.zoom.us/j/3458894777?omn=91979093447 Meeting ID: 345 889 4777 Physical compliance enters robotic systems either by design, to yield gracefully to disturbances, or by circumstance, as a property of the environment or task itself. Often this compliance is distributed across many interacting elements, and how those elements are connected determines whether their combined effect on the robot's […]
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High-throughput screening (HTS) is an essential step in the discovery and development of novel therapeutics. Single-phase and multiphase microfluidic platforms offer improved sensitivity, reduced cost, and enhanced physiological relevance compared with conventional screening technologies such as microplates and fluorescence-activated cell sorters. However, a challenge towards unlocking the full potential of microfluidic platforms for HTS in […]
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Zoom link: https://upenn.zoom.us/j/93917708817 Recent advances in learning-enabled control have dramatically expanded the capabilities of autonomous systems, with applications ranging from robots and self-driving cars to industrial automation systems. However, reliable real-world deployment remains fundamentally constrained by the uncertainty in learned components, the complexity of large-scale systems, and the high cost of collecting system data. Toward addressing […]
The growing demand for high-performance frequency control and power conversion systems has intensified research interest in piezoelectric MEMS resonators. This thesis investigates three piezoelectric material systems, including aluminum nitride (AlN), aluminum scandium nitride (AlScN), and lithium niobate (LiNbO₃), operating in different acoustic modes: bulk acoustic wave (BAW), thickness shear (TS), and Lamb wave modes, By […]
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Zoom Link: https://upenn.zoom.us/j/92477312796 Colloidal metal nanocrystals (NCs) are chemically synthesized, nanometer-scale metal particles whose surfaces are capped with organic or inorganic ligands to provide colloidal stability and solution processability. Metal NC dispersions can serve as inks for the solution-based deposition and patterning of conductors at lower thermal budgets and over large areas compared to processes […]
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Affecting 5-10% of infants worldwide, Cerebral Palsy (CP) is the most common motor disability among infants, presenting as a variety of motor, perception, and cognitive impairments. CP is a lifelong condition with no cure, but treatment exists through rehabilitation. Evidence suggests that rehabilitation can be especially effective before the age of 2, but to deliver […]
Zoom Link: https://upenn.zoom.us/j/98563756560?pwd=yXnuhaTv2V2jSOHzgiz1DujOa2Ubdw.1 Robots still have a lot to learn from animals when it comes to agile locomotion. Abstracting low-DOF dynamical models from animal locomotion and using them as control targets for robots has demonstrated impressive empirical results while often facilitating formal performance guarantees. However, implementations of this approach have historically tended to restrict their […]
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Two-dimensional (2D) materials offer a route to sustain semiconductor device scaling beyond the limits of silicon, providing atomically thin, dangling-bond-free channels and a versatile platform for further device scaling and the heterogeneous integration of electronic and optoelectronic functions. The principal bottleneck to their adoption, however, is the lack of a manufacturing route that simultaneously delivers […]
Mechanical metamaterials achieve extraordinary physical properties through their internal geometric architectures. While traditional metamaterials are limited by fixed designs, multistable reprogrammable metamaterials can modify these properties post-fabrication and morph into different shapes. However, existing tunable metamaterials often require continuous energy input, rely on global volumetric deformations, or necessitate complex actuation networks. In this talk, I […]
Abstract: Glass-forming, disordered materials are ubiquitous in our world. Systems lacking long-range order like a liquid but with many of the mechanical properties of a solid have countless applications and encompass many classes of materials, including polymers, which in many ways define the modern age. The use of glassy polymers to make membranes for separations […]
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This seminar will explore two complementary lines of research on the evolutionary transition from water to land. First, I will present new discoveries from the fossil record of early tetrapods that provide insight into how walking first evolved. Then, I will discuss how studies of mudskippers, small amphibious fishes that live in mangroves and on […]
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The Department of Bioengineering at the University of Pennsylvania and Dr. Ravi Radhakrishnan are pleased to announce the Doctoral Dissertation Defense of Mengdi Tao. Title: "Disease Modeling and Systems Pharmacology: Translating Molecular Mechanisms into Clinical Phenotypes using Virtual Population" Advisor: Dr. Ravi Radhakrishnan Date: Monday, July 27 Time: 9:00 AM - 10:30 AM Location: The […]
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Most mechanical failures are caused by fatigue, where damage accumulates gradually during sub-critical cyclic loading. Yet despite nearly two centuries of study, the microstructural origins of fatigue fracture remain elusive. Bioinspired hierarchical alloys enabled by additive manufacturing offer a promising route to systematically design fatigue-resistant materials. However, it remains unclear how discrete structural constituents independently […]
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The Department of Bioengineering at the University of Pennsylvania and Dr. Jennifer Phillips-Cremins are pleased to announce the Doctoral Dissertation Defense of Thomas Malachowski. Title: "Disease Modeling and Systems Pharmacology: Translating Molecular Mechanisms into Clinical Phenotypes using Virtual Population" Advisor: Dr. Jennifer Phillips-Cremins Date: Wednesday, July 29, 2026 Time: 3:00pm EST Location: The defense will […]
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In recent decades the use of soft materials as ‘active’ materials, especially as soft actuators for robotics applications, has grown. One thrust of work has focused on the use of porous elastomers, with direct control of the pore pressure as the actuation mechanism. Motivated by this interest, we investigate here the behavior of porous elastomeric […]
